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Saturday, June 21, 2008

Autonomic Neuroscience

Autonomic Neuroscience

Autonomic Neuroscience: Basic and ClinicalAdopted as the official publication of The International Society for Autonomic Neuroscience - External link http://www.isanweb.org
Former title: Journal of the Autonomic Nervous System


Description
The aim of the Journal is to stimulate, publish and disseminate original investigations on the autonomic nervous system: this includes the innervation of blood vessels and viscera, autonomic ganglia, efferent and afferent autonomic pathways, and autonomic nuclei and pathways in the central nervous system.


Free Access
Volume 138, Issues 1-2, Pages 1-118 (29 February 2008)

Basic Autonomic Neuroscience
1.Endogenous urea as an autacoid: Extrarenal and renal focuses
Pages 1-8
Nikolai D. Temnyalov
(276 K)
Clinical Autonomic Neuroscience
2.Putative mechanisms behind effects of spinal cord stimulation on vascular diseases: A review of experimental studies
Pages 9-23
Mingyuan Wu, Bengt Linderoth, Robert D. Foreman
(461 K)
Basic Autonomic Neuroscience
3.The baroreflex contribution to spontaneous heart rhythm assessed with a mathematical model in rats
Pages 24-30
Chiara Berteotti, Carlo Franzini, Pierluigi Lenzi, Elisa Magosso, Mauro Ursino, Giovanna Zoccoli, Alessandro Silvani
(366 K)
4.Neuropathological alteration of aquaporin 1 immunoreactive enteric neurons in the streptozotocin-induced diabetic rats
Pages 31-40
Eriko Ishihara, Masato Nagahama, Satoru Naruse, Reiji Semba, Toshihiro Miura, Masaru Usami, Masaaki Narita
(2248 K)
5.Non-NMDA and NMDA receptor agonists induced excitation and their differential effect in activation of superior salivatory nucleus neurons in anaesthetized rats
Pages 41-49
Ken'Ichi Ishizuka, Diana Oskutyte, Yoshihide Satoh, Toshiki Murakami
(870 K)
6.
Investigation of specificity of auricular acupuncture points in regulation of autonomic function in anesthetized rats
Pages 50-56
Xin-Yan Gao, Shi-Ping Zhang, Bing Zhu, Hong-Qi Zhang
(933 K)
7.Autonomic dysfunction in experimental sepsis induced by cecal ligation and puncture
Pages 57-63
João Alexandre Trés Pancoto, Pollyanna Barbosa Farias Corrêa, Gabriela Ravanelli Oliveira-Pelegrin, Maria José Alves Rocha
(496 K)
8.Topography of the porcine epicardiac nerve plexus as revealed by histochemistry for acetylcholinesterase
Pages 64-75
Darius Batulevicius, Valdas Skripka, Neringa Pauziene, Dainius H. Pauza
(2347 K)
9.Hypoxia-induced vasodilation in the right coronary circulation of conscious dogs: Role of adrenergic activation
Pages 76-82
Srinath Setty, Pu Zong, Wei Sun, Johnathan D. Tune, H. Fred Downey
(235 K)
10.
Ionotropic glutamate receptor expression in preganglionic neurons of the rat inferior salivatory nucleus
Pages 83-90
M. Kim, D.J. Chiego Jr., R.M. Bradley
(1466 K)
11.Effects of electroacupuncture on gastric motility and heart rate variability in conscious rats
Pages 91-98
Kenji Imai, Hajime Ariga, Cindy Chen, Christopher Mantyh, Theodore N. Pappas, Toku Takahashi
(517 K)
12.Muscle receptors close to the myotendinous junction play a role in eliciting exercise pressor reflex during contraction
Pages 99-107
Tomoko Nakamoto, Kanji Matsukawa
(477 K)
13.Cardiovascular autonomic regulation in Non-Obese Diabetic (NOD) mice
Pages 108-113
Volkmar Gross, Jens Tank, Hans-Joachim Partke, Ralph Plehm, André Diedrich, Andrey C. da Costa Goncalves, Friedrich C. Luft, Jens Jordan
(651 K)
Clinical Autonomic Neuroscience
14.Diminished baroreflex-induced vasoconstriction following alpha-2 adrenergic receptor blockade in humans
Pages 114-117
D. Walter Wray, Peter B. Raven, Mikael Sander
(154 K)
15.Notes To Authors
Page I
(43 K)

http://www.sciencedirect.com/science/journal/15660702

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Appetite

Appetite



Description
Appetite is an international research journal specializing in behavioural nutrition and the cultural, sensory, and physiological influences on choices and intakes of foods and drinks. It covers normal and disordered eating and drinking, dietary attitudes and practices and all aspects of the bases of human and animal behaviour toward food.

The journal carries short communications, book reviews and abstracts from major meetings in the social science, psychology or neuroscience of food consumption, including the Association for the Study of Food in Society, the Society for the Study of Ingestive Behavior, and conferences on Food Choice.

Research Areas Include:


• Preventive, experimental and clinical nutrition
• Eating disorders
• Sensory evaluation of foods
• Food attitudes and marketing
• Ethnography of food habits
• Psychology of ingestion
• Zoology of foraging
• Neuroscience of feeding and drinking

Free Access
Volume 50, Issues 2-3, Pages 181-568 (March-May 2008)

Research Review
1.How emotions affect eating: A five-way model
Pages 1-11
Michael Macht
(249 K)
Research Reports
2.Television use and food choices of children: Qualitative approach
Pages 12-18
Giovanna Medeiros Rataichesck Fiates, Renata D.M.C. Amboni, Evanilda Teixeira
(168 K)
3.Repeated cue exposure effects on subjective and physiological indices of chocolate craving
Pages 19-24
Dinska Van Gucht, Debora Vansteenwegen, Tom Beckers, Dirk Hermans, Frank Baeyens, Omer Van den Bergh
(163 K)
4.Validation of a scale for the assessment of food cravings among smokers
Pages 25-32
Benjamin A. Toll, Nicole A. Katulak, Pamela Williams-Piehota, Stephanie O’Malley
(196 K)
5.Food, eating, and weight concerns of men in recovery from substance addiction
Pages 33-42
Jennifer Cowan, Carol Devine
(199 K)
6.Sensitivity to reward and body mass index (BMI): Evidence for a non-linear relationship
Pages 43-49
Caroline Davis, John Fox
(195 K)
7.Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males
Pages 50-56
Giovanni Addolorato, Lorenzo Leggio, Veronica Ojetti, Esmeralda Capristo, Giovanni Gasbarrini, Antonio Gasbarrini
(174 K)
8.Front-of-pack nutrition labelling: Testing effectiveness of different nutrition labelling formats front-of-pack in four European countries
Pages 57-70
Gerda I.J. Feunekes, Ilse A. Gortemaker, Astrid A. Willems, René Lion, Marcelle van den Kommer
(362 K)
9.Enhanced salt appetite, diet and drinking in traditional Bedouin women in the Negev
Pages 71-82
Micah Leshem, Amany Saadi, Nesreen Alem, Khadeja Hendi
(226 K)
10.
Structure of the relationship between parents’ and children's food preferences and avoidances: An explorative study
Pages 83-90
Margherita Guidetti, Nicoletta Cavazza
(219 K)
11.Experimental investigation of the effects of naturalistic dieting on bulimic symptoms: Moderating effects of depressive symptoms
Pages 91-101
Katherine Presnell, Eric Stice, Jennifer Tristan
(223 K)
12.Emotional responses to food, body dissatisfaction and other eating disorder features in children, adolescents and young adults
Pages 102-109
Caroline McNamara, Phillipa Hay, Mary Katsikitis, Anna Chur-Hansen
(170 K)
13.Is the desire to eat familiar and unfamiliar meat products influenced by the emotions expressed on eaters’ faces?
Pages 110-119
S. Rousset, P. Schlich, A. Chatonnier, L. Barthomeuf, S. Droit-Volet
(864 K)
14.The role of implicit wanting in relation to explicit liking and wanting for food: Implications for appetite control
Pages 120-127
Graham Finlayson, Neil King, John Blundell
(180 K)
15.Deconstructing the vanilla milkshake: The dominant effect of sucrose on self-administration of nutrient–flavor mixtures
Pages 128-138
Amy M. Naleid, Jeffrey W. Grimm, David A. Kessler, Alfred J. Sipols, Sepideh Aliakbari, Jennifer L. Bennett, Jason Wells, Dianne P. Figlewicz
(989 K)
16.Decreasing dislike for sour and bitter in children and adults
Pages 139-145
Elizabeth D. Capaldi, Gregory J. Privitera
(204 K)
17.Quest for social safety in imported foods in China: Gatekeeper perceptions
Pages 146-157
John Knight, Hongzhi Gao, Tony Garrett, Ken Deans
(234 K)
18.Modulation of biting procedures induced by the sensory evaluation of cheese hardness with different definitions
Pages 158-166
Haruka Dan, Fumiyo Hayakawa, Kaoru Kohyama
(225 K)
19.Engaging with healthy eating discourse(s): Ways of knowing about food and health in three ethnocultural groups in Canada
Pages 167-178
Svetlana Ristovski-Slijepcevic, Gwen E. Chapman, Brenda L. Beagan
(216 K)
20.Erratum to “Curt Richter: A life in the laboratory, Jay Schulkin (Ed.); Johns Hopkins University Press, Baltimore, Maryland, 2005, Cost US$49.95. ISBN 0-8018-8073-4.”: [Appetite 45 (2005) 360–361]
Page 179
Gerard P. Smith
(71 K)
21.Calendar of Events
Page 180
(59 K)

http://www.sciencedirect.com/science/journal/01956663

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Alzheimer's & Dementia Suppliment

Alzheimer's & Dementia Suppliment

Free access
Volume 4, Issue 1, Supplement 1, Pages A1-A8, S1-S168 (January 2008)

Contents Page A3
PDF (39 K)
3. Contents
Page A4
PDF (49 K)
4. Editorial board
Page A5
PDF (36 K)
5. Medical and scientific advisory council
Page A6
PDF (32 K)
Editorial
6. Leon Joel Thal, MD, 1944–2007: Honoring his scientific legacy
Pages S1-S3
Zaven S. Khachaturian
PDF (67 K)
Perspectives
7. Leon Thal and the therapeutic age of Alzheimer’s disease
Pages S4-S6
Paul S. Aisen
PDF (75 K)
8. Chronic disease long-term drug prevention trials: Lessons from the Alzheimer’s Disease Anti-inflammatory Prevention Trial (ADAPT)
Pages S7-S14
Curtis L. Meinert, John C.S. Breitner
PDF (130 K)
9. Optimizing phase II of drug development for disease-modifying compounds
Pages S15-S20
Jeffrey L. Cummings
PDF (289 K)
10.
We should not distinguish between symptomatic and disease-modifying treatments in Alzheimer’s disease drug development
Pages S21-S25
Rachelle S. Doody
PDF (89 K)
11. Drug discovery and the prevention of Alzheimer’s disease
Pages S26-S28
Howard Fillit
PDF (79 K)
12. Realizing the potential of positron emission tomography with 18F-fluorodeoxyglucose to improve the treatment of Alzheimer’s disease
Pages S29-S36
Norman L. Foster, Angela Y. Wang, Tolga Tasdizen, P. Thomas Fletcher, John M. Hoffman, Robert A. Koeppe
PDF (2125 K)
13. Eyes on the prize: Federal Alzheimer’s research effort aims to facilitate interventions
Pages S37-S47
Richard J. Hodes, Neil Buckholtz, Vicky Cahan, Marcelle Morrison-Bogorad
PDF (159 K)
14. Current and future management of Alzheimer’s disease
Pages S48-S50
Serge Gauthier, Judes Poirier
PDF (77 K)
15. A quarter century of advancing treatment for Alzheimer’s disease with Leon J. Thal
Pages S51-S55
Michael Grundman
PDF (100 K)
16. The oldest old and the 90+ Study
Pages S56-S59
Claudia H. Kawas
PDF (109 K)
17. Home-based technologies: A new paradigm for conducting dementia prevention trials
Pages S60-S66
Jeffrey Kaye
PDF (427 K)
18. Differentiating Alzheimer’s disease from dementia with Lewy bodies and Parkinson’s disease with (+)-[11C]dihydrotetrabenazine positron emission tomography
Pages S67-S76
Robert A. Koeppe, Sid Gilman, Larry Junck, Kris Wernette, Kirk A. Frey
PDF (1081 K)
19. Dementia: Is it time for a change in focus?
Pages S77-S84
Lewis H. Kuller, Oscar L. Lopez
PDF (125 K)
20. A perspective on risks that impede development of drugs to modify the course of Alzheimer’s disease: Can they be reduced?
Pages S85-S87
Richard C. Mohs
PDF (82 K)
21. Challenges in clinical research on Alzheimer’s disease: Leon Thal’s legacy
Pages S88-S90
Ronald C. Petersen
PDF (76 K)
22. Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer’s disease
Pages S91-S97
Judes Poirier
PDF (314 K)
23. The pre–mild cognitive impairment, subjective cognitive impairment stage of Alzheimer’s disease
Pages S98-S108
Barry Reisberg, Leslie Prichep, Lisa Mosconi, E. Roy John, Lidia Glodzik-Sobanska, Istvan Boksay, Isabel Monteiro, Carol Torossian, Alok Vedvyas, Nauman Ashraf, Imran A. Jamil, Mony J. de Leon
PDF (1881 K)
24. Disease-modifying approaches to Alzheimer’s disease: Challenges and opportunities—Lessons from donepezil therapy
Pages S109-S118
Marwan N. Sabbagh, Sharon Richardson, Norman Relkin
PDF (216 K)
25. Current challenges for the successful treatment and prevention of Alzheimer’s disease: Treating the pathologies of the disease to change its clinical course
Pages S119-S121
Dale Schenk
PDF (69 K)
26. Prevention therapeutics of dementia
Pages S122-S130
Lon S. Schneider
PDF (137 K)
27. More than a decade of estrogen neuroprotection
Pages S131-S136
James W. Simpkins, Meharvan Singh
PDF (129 K)
28. Electroencephalography and event-related potentials as biomarkers of mild cognitive impairment and mild Alzheimer’s disease
Pages S137-S143
Colleen E. Jackson, Peter J. Snyder
PDF (130 K)
29. Memory health clinics—a first step to prevention
Pages S144-S149
Bruno Vellas, Sophie Gillette-Guyonnet, Sandrine Andrieu
PDF (109 K)
30. Leon Thal’s vision for the treatment and prevention of Alzheimer’s disease
Pages S150-S152
Michael W. Weiner
PDF (72 K)
31. Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses
Pages S153-S168
Mehmet Cansev, Richard J. Wurtman, Toshimasa Sakamoto, Ismail H. Ulus
PDF (1100 K)

http://www.sciencedirect.com/science/journal/15525260

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Alzheimer's & Dementia

Alzheimer's & Dementia

Free access issue
Volume 4, Issue 1, Pages A1-A8, 1-64 (January 2008)


Contents Page A3
(63 K)
3. Editorial
Page A5
(36 K)
4. Medical and scientific advisory council
Page A6
(32 K)
Perspectives
5. Exploring human/animal intersections: Converging lines of evidence in comparative models of aging
Pages 1-5
John Q. Trojanowski, Joan C. Hendricks, Kathryn Jedrziewski, F. Brad Johnson, Kathryn E. Michel, Rebecka S. Hess, Michael P. Cancro, Meg M. Sleeper, Robert Pignolo, Karen L. Teff, Gustavo D. Aguirre, Virginia M.-Y. Lee, Dennis F. Lawler, Allan I. Pack, Peter F. Davies
(80 K)
Featured Articles
6. Elevated microsomal prostaglandin-E synthase–1 in Alzheimer’s disease
Pages 6-13
Uzma A. Chaudhry, Hean Zhuang, Barbara J. Crain, Sylvain Doré
(2207 K)
7. Practicality of a computerized system for cognitive assessment in the elderly
Pages 14-21
Howard M. Fillit, Ely S. Simon, Glen M. Doniger, Jeffrey L. Cummings
(637 K)
8. Prognosis of Alzheimer’s disease today: A two-year prospective study in 686 patients from the REAL-FR Study
Pages 22-29
Frédéric Cortes, Fati Nourhashémi, Olivier Guérin, Christelle Cantet, Sophie Gillette-Guyonnet, Sandrine Andrieu, Pierre-Jean Ousset, Bruno Vellas and REAL-FR Group
(194 K)
9. One-week dose titration of extended release galantamine in patients with Alzheimer’s disease
Pages 30-37
Douglas W. Scharre, Thomas Shiovitz, Young Zhu, Joan Amatniek
(276 K)
Review Articles
10. Core candidate neurochemical and imaging biomarkers of Alzheimer’s disease
Pages 38-48
Harald Hampel, Katharina Bürger, Stefan J. Teipel, Arun L.W. Bokde, Henrik Zetterberg, Kaj Blennow
(776 K)
11. Behavioral effects of current Alzheimer’s disease treatments: A descriptive review
Pages 49-60
Jeffrey L. Cummings, Joan Mackell, Daniel Kaufer
(163 K)
Association Pages
12. Alzheimer’s Association Update
Pages 61-63
(75 K)

http://www.sciencedirect.com/science/journal/15525260

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Friday, June 20, 2008

Advanced Drug Delivery Reviews

Advanced Drug Delivery Reviews

The aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine. The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery.

In general, the Journal publishes review articles in a Theme Issue format. Each Theme Issue provides a comprehensive and critical examination of current and emerging research on the design and development of advanced drug and gene delivery systems and their application to experimental and clinical therapeutics. The goal is to illustrate the pivotal role of a multidisciplinary approach to modern drug delivery, encompassing the application of sound biological and physicochemical principles to the engineering of drug delivery systems to meet the therapeutic need at hand.

Articles review the current status of a specific topic, giving equal emphasis to the identification of major conceptual and technological challenges to successful drug and gene delivery, to an evaluation of triumphs as well as shortcomings in current conceptual and technical approaches, and to a discussion of their possible solution.

Free access
Volume 60, Issue 1, Pages 1-88 (3 January 2008)

Peptide and Protein PEGylation III: Advances in Chemistry and Clinical Applications
Edited by Francesco M. Veronese and J. Milton Harris
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1.Editorial Page ii
PDF (53 K)
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Peptide and protein PEGylation III: advances in chemistry and clinical applications
Pages 1-2
Francesco M. Veronese, J. Milton Harris
PDF (104 K)
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Disulfide bridge based PEGylation of proteins
Pages 3-12
Steve Brocchini, Antony Godwin, Sibu Balan, Ji-won Choi, Mire Zloh, Sunil Shaunak
PDF (444 K)
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Site-specific modification and PEGylation of pharmaceutical proteins mediated by transglutaminase
Pages 13-28
Angelo Fontana, Barbara Spolaore, Anna Mero, Francesco M. Veronese
PDF (1160 K)
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Releasable PEGylation of proteins with customized linkers
Pages 29-49
David Filpula, Hong Zhao
PDF (1823 K)
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Formulation of Neulasta® (pegfilgrastim)
Pages 50-58
Deirdre Murphy Piedmonte, Michael J. Treuheit
PDF (279 K)
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PEG-uricase in the management of treatment-resistant gout and hyperuricemia
Pages 59-68
Merry R. Sherman, Mark G.P. Saifer, Fernando Perez-Ruiz
PDF (658 K)
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Anti-cancer PEG-enzymes: 30 years old, but still a current approach
Pages 69-78
Gianfranco Pasut, Mauro Sergi, Francesco M. Veronese
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PEGylation of cyanovirin–N, an entry inhibitor of HIV
Pages 79-87
H. Zappe, M.E. Snell, M.J. Bossard
PDF (603 K)

http://www.sciencedirect.com/science/journal/0169409X

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Acute Pain

Acute Pain

Free access
Volume 10, Issue 1, Pages 1-58 (March 2008)

Table of content:

1. Editorial Board Page CO2
PDF (1229 K)
Articles
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A benchmark of 3 years experiences in acute pain service at Srinagarind hospital
Pages 1-8
Malinee Wongswadiwat, Wimonrat Sriraj, Panaratana R. Yimyaem, Suthannee Simajareuk, Somboon Thienthong
PDF (406 K)
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An evaluation of postoperative epidural analgesia in acute pain service in an Indian cancer hospital (a preliminary experience of patient satisfaction survey)
Pages 9-14
P.N. Jain, Sheila N. Myatra, Anagha C. Kakade, R. Sareen
PDF (499 K)
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Indications and contraindications for thoracic epidural analgesia in multiply injured patients
Pages 15-22
Eileen M. Bulger, William T. Edwards, Mario de Pinto, Patricia Klotz, Gregory J. Jurkovich
PDF (562 K)
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Magnesium sulphate pretreatment to alleviate pain on propofol injection: A comparison with ketamine or lidocaine
Pages 23-29
Azim Honarmand, Mohammadreza Safavi
PDF (129 K)
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How patients and physicians rate patients’ pain in a French emergency department using a verbally administered numerical rating scale and a visual analog scale
Pages 31-37
Laetitia Marquié, Liliana Rico Duarte, Claudette Mariné, Dominique Lauque, Paul Clay Sorum
PDF (322 K)
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Continuous paravertebral block for pain relief in unilateral multiple rib fracture: A case series
Pages 39-44
Aditya Nath Shukla, Zainab Bt Abdul Ghaffar, Ang Chin Auang, Usha Rajah, Lawrance Tan
PDF (149 K)
Abstracts
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Oral transmucosal fentanyl citrate for the treatment of breakthrough pain: Results of a non-interventional study (NIS)
Page 45
R. Zarth, M. Ehmer, H.-B. Sittig
PDF (66 K)
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Management of vasoocclusive pain events in sickle cell disease
Pages 45-46
A.M. Ellison, K. Shaw
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Control of pain during transrectal ultrasound-guided prostate biopsy: A prospective study comparing two methods
Page 46
K.K. Bhomi, H.H. Lim, D.T. Consigliere, H.Y. Tiong
PDF (39 K)
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The efficacy of lidocaine-prilocaine cream to reduce pain in genetic amniocentesis
Page 46
D. Pongrojpaw, C. Somprasit, A. Chanthasenanont
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Pain evaluation in outpatients undergoing diagnostic anesthesia-free hysteroscopy in a teaching hospital: A cohort study
Page 47
J.A. de Carvalho Schettini, M.M. Ramos de Amorim, A.A. Ribeiro Costa, L.C. Albuquerque Neto
PDF (37 K)
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Medication errors with opioids: Results from a national reporting system
Pages 47-48
S.M. Dy, A.D. Shore, R.W. Hicks, L.L. Morlock
PDF (44 K)
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Perioperative auricular electroacupuncture has no effect on pain and analgesic consumption after third molar tooth extraction
Page 48
A. Michalek-Sauberer, H. Heinzl, S.M. Sator-Katzenschlager, G. Monov, E. Knolle, H.G. Kress
PDF (37 K)
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Dexamethasone for reduction of nausea, vomiting and analgesic use after gynecological laparoscopic surgery
Page 48
Y. Fujii, M. Nakayama
PDF (37 K)
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Clinical analgesic efficacy and side effects of dexmedetomidine in the early postoperative period after arthroscopic knee surgery
Page 49
M.E. Gomez-Vazquez, E. Hernandez-Salazar, A. Hernandez-Jimenez, A. Perez-Sanchez, V.A. Zepeda-Lopez, M. Salazar-Paramo
PDF (39 K)
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Parecoxib sodium administered over several days reduces pain after gynecologic surgery via laparotomy
Pages 49-50
M.C. Snabes, A.J. Jakimiuk, J. Kotarski, T.K. Katz, M.T. Brown, K.M. Verburg
PDF (47 K)
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Reduction of postoperative nausea and vomiting and analgesic requirement with dexamethasone in women undergoing general anesthesia for mastectomy
Page 50
Y. Fujii, M. Nakayama
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Peripherally acting opioid antagonists in the treatment of opiate-related constipation: A systematic review
Page 50
G. Becker, D. Galandi, H.E. Blum
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A randomized controlled trial of perioperative administration of pregabalin for pain after laparoscopic hysterectomy
Page 51
R. Jokela, J. Ahonen, M. Tallgren, M. Haanpaa, K. Korttila
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Mathematical analysis of involvement ratio between central and peripheral COX-2 in rat pain models with two types of COX-2 inhibitors with different distribution, celecoxib and CIAA
Page 51
T. Okumura, A. Sakakibara, Y. Murata, Y. Kita
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Pregabalin: Its pharmacology and use in pain management
Pages 51-52
N.M. Gajraj
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Cardiovascular thromboembolic adverse effects associated with cyclooxygenase-2 selective inhibitors and nonselective antiinflammatory drugs
Page 52
G.P. Joshi, R. Gertler, R. Fricker
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The pharmacogenetics of analgesia
Page 52
U.M. Stamer, F. Stuber
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Focused analgesia in waking and hypnosis: Effects on pain, memory, and somatosensory event-related potentials
Page 53
V. De Pascalis, I. Cacace, F. Massicolle
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Emotional valence contributes to music-induced analgesia
Page 53
M. Roy, I. Peretz, P. Rainville
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Local anesthetic treatment significantly attenuates acute pain responding but does not prevent the neonatal injury-induced reduction in adult spinal behavioral plasticity
Page 54
E.E. Young, K.M. Baumbauer, J. Hillyer, R.L. Joynes
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Acute pain at discharge from hospitalization is a prospective predictor of long-term suicidal ideation after burn injury
Pages 54-55
R.R. Edwards, G. Magyar-Russell, B. Thombs, M.T. Smith, R.K. Holavanahalli, D.R. Patterson, P. Blakeney, D.C. Lezotte, J.A. Haythornthwaite, J.A. Fauerbach
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Long-term pain after inguinal hernia repair in a population-based cohort; risk factors and interference with daily activities
Page 55
M.-L. Kalliomaki, J. Meyerson, U. Gunnarsson, T. Gordh, G. Sandblom
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Analgesic efficacy of orodispersible paracetamol in patients admitted to the emergency department with an osteoarticular injury
Pages 55-56
A. Viallon, O. Marjollet, P. Guyomarch, F. Robert, C. Berger, S. Guyomarch, M.L. Navez, J.-C. Bertrand
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Acute pain management in emergency medicine
Page 56
M. Galinski, F. Adnet
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A randomized controlled trial of femoral nerve blockade administered preclinically for pain relief in femoral trauma
Pages 56-57
A. Schiferer, C. Gore, L. Gorove, T. Lang, B. Steinlechner, M. Zimpfer, A. Kober
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Femoral nerve block for diaphyseal and distal femoral fractures in the emergency department
Page 57
C.E. Mutty, E.J. Jensen, M.A. Manka Jr., M.J. Anders, L.B. Bone
PDF (37 K)
34. You are entitled to access the full text of this document
The utility of pain assessment for analgesic use in persons with dementia
Pages 57-58
J. Cohen-Mansfield, S. Lipson
PDF (47 K)
35. You are entitled to access the full text of this document
A systematic review of non-pharmacological pain management methods for premature infants
Page 58
G. Paquette, S. Le May, M. Aita
PDF (38 K)
36. You are entitled to access the full text of this document
Conference Calendar
Pages II-IV
PDF (71 K)

http://www.sciencedirect.com/science/journal/13660071

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Disease a Month

Disease-a-Month



Description

Designed for primary care physicians, each issue of Disease-a-Month presents an in-depth review of a single topic. In this way, the publication can cover all aspects of the topic-pathophysiology, clinical features of the disease or condition, diagnostic techniques, therapeutic approaches, and prognosis.

Disease-a-Month has an Impact Factor of 1.618 in the 2005 ISI Journal Citation Reports®, published by Thomson Scientific.


Free access:
Volume 54, Issues 1-2, Pages 1-156 (January-February 2008)

Contact Allergy: Alternatives for the
2007 North American Contact
Dermatitis Group (NACDG) Standard
Screening Tray
Foreword 6
Contact Allergy: Alternatives for the 2007 North American
Contact Dermatitis Group (NACDG) Standard Screening Tray 7
Introduction 7
Cosmetic Contact Allergy 11
Part I: Fragrances and Related Oral Allergens 11
Fragrance 11
Fragrance Mix, Cinnamic Aldehyde 12
Balsam of Peru 14
Benzyl Alcohol 15
Botanical Fragrances 16
Compositae and Sesquiterpenlactone Mixes 16
Tea Tree Oil 18
Ylang Ylang Oil 19
Propolis 20
Fragrance-Free Products 20
Oral Exposure to Fragrance-Related Substances 21
Part II: Non-Fragrance Allergens in Skin, Hair, Cosmetic, Nail,
and Oral Products
66
Parabens 66
Formaldehyde-Releasing Preservatives 66
Kathon CG (Methylisothiazolinone, Methylchloroisothiazolinone) 67
Euxyl K400 (Methyldibromoglutaronitrile/Phenoxyethanol) 68
Iodopropynylbutylcarbamate 68
Preservatives Hidden in Herbal Extracts 68
Cocamidopropyl Betaine, Amidoamine 69
Propylene Glycol 70
Lanolin and Wool Alcohol 71
Oxybenzone 74
Vitamin E 75
Cocamide DEA 75


http://www.sciencedirect.com/science/journal/00115029

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Thursday, June 19, 2008

Blackwell Synergy will no longer be available

Blackwell Synergy will no longer be available

Transfer of journal content from Blackwell Synergy to Wiley InterScience
from June 30th 2008.


From June 30th 2008 the journal content currently available on Blackwell Synergy www.blackwellsynergy.com will be delivered through Wiley InterScience www.interscience.wiley.com due to the merger of Wiley-Blackwell's online journal systems.

This is a first step in the development of a next generation online publishing platform, arriving early 2009, which will deliver Wiley-Blackwell journals, online books, reference works, databases, protocols and other electronic resources through one integrated service.

The benefits will begin immediately after June 30th:

* One-stop access to a dramatically expanded range of relevant material
* approximately 3 million articles
* 1400 journals
* 5000 online books, reference works and databases

Wednesday, June 18, 2008

Heart Diseases

Heart Diseases

There are over 5600 articles published on the subject and can be accessed freely.

A Joint report by the Rheumatic Fever Working Party of the Medical Research Council of Great Britain and the Subcommittee of Principal Investigators of the American Council on Rheumatic Fever and Congenital Heart Disease, American Heart Association.

The Natural History of Rheumatic Fever and Rheumatic Heart Disease: Ten-Year Report of a Cooperative Clinical Trial of ACTH, Cortisone, and Aspirin
Circulation 1965 32: 457-476. [PDF]

David A. Clayton, R. Sanders Williams, and Isabella Y. Liang
Meeting Highlights
Circulation 1995 92: 2022-2023. [Full Text]

Ariane Marelli
Congenital Heart Disease in Adults : Joseph K. Perloff, MD and John S. Child, MD. 406 pp.Philadelphia, Pa: WB Saunders; 1997. $110.00. ISBN 0-7216-2998-9.
Circulation 1998 98: 1039a-1040a. [Full Text]

JACQUES M. SMITH, JEREMIAH STAMLER, ROBERT A. MILLER, MILTON H. PAUL, IRVING ABRAMS, RAYMOND M. RESTIVO, and LOUIS DEBOER
The Detection of Heart Disease in Children: Results of Mass Field Trials with Use of Tape Recorded Heart Sounds. III. The Chicago Area High School Study
Circulation 1965 32: 966-976. [PDF]

TS Klitzner
Sudden cardiac death in children
Circulation 1990 82: 629-632. [PDF]

J. Thomas Bigger, Jr, Joseph L. Fleiss, Richard C. Steinman, Linda M. Rolnitzky, William J. Schneider, and Phyllis K. Stein
RR Variability in Healthy, Middle-Aged Persons Compared With Patients With Chronic Coronary Heart Disease or Recent Acute Myocardial Infarction
Circulation 1995 91: 1936-1943. [Full Text]

Steven A. Webber
New-Onset Heart Failure in Children in the Absence of Structural Congenital Heart Disease
Circulation 2008 117: 11-12. [PDF]

KATHRYN H. EHLERS and MARY ALLEN ENGLE
Familial Congenital Heart Disease: I. Genetic and Environmental Factors
Circulation 1966 34: 503-516. [PDF]

MD Freed, MA Heymann, AB Lewis, SL Roehl, and RC Kensey
Prostaglandin E1 infants with ductus arteriosus-dependent congenital heart disease
Circulation 1981 64: 899-905. [PDF]

For full list of articles visit here.
http://www.ahajournals.org/cgi/bbtBrowse?subdir_name=ahajournals_bbt&category=3162669

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Tuesday, June 17, 2008

Drug Design Software and Tools

Drug Design Software and Tools from Supercomputing Facility for Bioinformatics & Computational Biology, IIT, Delhi

1. Binding Affinity Prediction of Protein-Ligand Server(BAPPL)
Computes the binding free energy of a protein-ligand complex.

2. Binding Affinity Prediction of Protein-Ligand complex containing Zinc Server (BAPPL-Z)
Computes the binding free energy of a metalloprotein-ligand complex containing zinc.

3. Drug-DNA Interaction Energy (PreDDICTA)
Calculates the Drug-DNA interaction energy.

4. ParDOCK - Automated Server for Rigid Docking
Predicts the binding mode of the ligand in receptor target site.

5. Non Redundant Database of Small Molecules
Virtual high throughput screening of small molecules and their optimization into lead- like candidates.

6. Lipinski Filters
Checks whether a drug satisfies the 5 Lipinski rules.

7. Molecular Volume Calculator
Calculates the volume of a molecule

Research Journal of Phytochemistry 2007

Research Journal of Phytochemistry 2007

Phytochemical Investigation and Biological Evaluation of Schinus terebinthifolius

Alcoholic extract of the aerial parts of Schinus terebinthifolius exhibit significant antioxidant, antifungal, antialzheimer`s and antileishmanicidal activities. Investigation of the chemical constituents of this plant let to isolate one new naturally occurring compound, synthetically known named (4-aminophenyl) acetic acid, along with the known 2-phenylacetamide, 1-pentadecanol, 3-(4-aminophenyl) prop-2-enoic acid, (E), ethyl 3, 4, 5-trihydroxybenzoate, cinnamic acid and benzamide. The structures of these compounds were established by spectroscopy techniques, including 1D and 2D NMR spectroscopy and comparison with the published data. The structure of (4-aminophenyl) acetic acid has also been confirmed by X-ray diffraction studies. The total alcoholic extract of Schinus terebinthifolius was evaluated for several bioassay activities and the isolated compounds were evaluated for their antifungal and antioxidant activities.

Physiological Response of Amaranthus cruentus and Oryza sativa to Phytotoxins of Tithonia diversifolia

The understanding of the inhibitory effect that Tithonia diversifolia (Hemsl) A. Gray can cause to nutrient accumulation of associated crops in the field is required to substantiate the need for effective control of the weed. The susceptibility of Amaranthus cruentus and Oryza sativa Linn. to phytotoxic effects of Tithonia diversifolia, the phytotoxicity of the plant parts of T. diversifolia and also the effect of drying on the phytotoxic activity of the weed were determined. The effects of the aqueous extracts prepared from the shoots and roots of T. diversifolia on Amaranthus cruentus and Oryza sativa were obtained by subjecting the seedlings to the different aqueous extract treatments. Results showed that chlorophyll accumulation and total protein contents of test plants were retarded by all the four different aqueous extracts applied. The retardation was more pronounced in older plants. The degree of retardatory effects of the aqueous extracts were found to follow this order: Fresh shoot aqueous extract (FSE) > dry shoot aqueous extract (DSE)>fresh root aqueous extract (FRE)>dry root aqueous extract (DRE). There was a significantly higher phytotoxic potency at p<>

Phytochemical Investigation and -Cellulose Content Determination of Gazania splendens Moore

Chemical constituents investigation of Gazania splendens Moore (Compositae family) let to isolate two flavonoids via luteolin and luteolin 7-O-glucoside, 11 n-alkanes (C14-C30), ß-amyrin, cholesterol, ß-sitosterol, stigmasterol and eight fatty acids. The structures of these compounds were established by Mass Spectrometry (MS), Gas-Liquid Chromatography (GLC) and spectroscopic techniques, including Ultra-violet (UV), Infra-Red (IR). The percentage of cellulose content in the leaves and flowers of the plant were 70.50 and 73.11%, respectively, hence the percentage in whole plant was 71.81%.

Phytochemical Screnning and Mineral Contents of Leaves of Some Nigerian Woody Plants

In this study, leaves of woody plants (2-4 species) obtained in Nigeria between November and December 2001 was evaluated for their phytochemical and mineral contents using standard methods. To determine minerals, 0.5 g of each samples were dry ashed, dissolved in distilled water with few drops of conc. HCL and read on an atomic absorption spectrophotometer. Phytate and phytate P were analyzed by first extracting the samples followed by titrating with FeCl3, the values obtained were multiplied with standard factors (1.95 and 3.56, respectively) and qualitative methods were used for other tests. The study revealed presence of alkaloids, tannins, resins, saponins, flavonoids, glycosides, carbohydrate, sterols and flobatanin in most of the samples. The levels of phytate (mean = 692, SD = 212, CV% = 30.7) and phytate phosphorous (mean = 188, SD = 51, CV% = 27.4) were generally high and all leaves had more than 30% of their total phosphorus linked to phytate. These results compared with literature values. The concentrations of the mineral were found to be high. The result showed that with high phytate contents the bioavailability of minerals might be relatively low.

Dihydronaphtalenone and Chromone from Cassia petersiana Bolle and the Antisalmonellal Activity of its Crude Extract

Phytochemical investigation of the leaves of C. petersiana afforded two new compounds (4 α-Acetyl-3,7-dihydroxy-3,6-dimethyldihydronaphtalenone and 5-Hydroxy -7- acetonyl -2-methylenechromone), in addition to common terpenes as sitosterol, stigmasterol glucoside. The crude extract and the new compounds were tested for antisalmonellal activity. The structures of the compounds were determined from comprehensive NMR studies, including 1H, 13C, DEPT, COSY, HMQC, HMBC, MS, IR and comparison with literature data.

HPTLC Method for the Quantification of Plumbagin in Three Plumbago Species

Plumbagin is a naturally occurring naphthoquinone, found in abundance in the genus Plumbago. A simple, sensitive, selective, precise and robust HPTLC quantitative method of analysis of plumbagin has been developed and validated. The quantity of plumbagin in the crude extracts, obtained from the three common species of Plumbago namely, Plumbago zeylanica, Plumbago rosea and Plumbago capensis has been determined. Total Plumbagin content of P. rosea, P. capensis and P. zeylanica was found to be 0.569, 0.429 and 0.247 mg%, respectively. Densitometric analysis of Plumbagin was carried out in the absorbance mode at 265 nm. This method gave compact spots at Rf = 0.78 corresponding to plumbagin. The linear regression analysis data for the calibration plots for Plumbagin had shown good linear relationship with R2 = 0.998±0.0035 in the concentration range of 20-80 ng/spot. The method was validated for robustness and precision. The limit of detection is noticed to be of 2 ng and is statistically tested for repeatability by inter day and intra day precision tests as per ICH guidelines and its updated international convention. Since this method resolves and quantifies Plumbagin effectively, it can be used to quantify the concentration of Plumbagin in the herbal preparations.

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Research Journal of Phytochemistry 2008

Research Journal of Phytochemistry 2007

HPTLC Method for Estimation of Ellagic Acid and Gallic Acid in Triphala churanam Formulations

Churanams are important group of formulations used by traditional physicians to treat various types of diseases. Triphala churanam, as per Siddha literature is used for the treatment of wounds and local ulcers. In the present study, an attempt has been made to develop a HPTLC (High Performance Thin Layer Chromatography) method of quantitative estimation of marker compounds, ellagic acid and gallic acid in laboratory prepared authentic formulation and a commercial formulation of Triphala churanam. The two formulations were subjected to methanol and ethyl acetate extractions by using Soxhlet apparatus. Ellagic acid and gallic acid were quantified in the above two extracts by using HPTLC. The detection and quantification were performed at a wavelength of 280 nm. The laboratory formulation was found to contain 0.201% w/w of ellagic acid and 0.656% w/w of gallic acid in methanol extract while it shows 0.573% w/w of ellagic acid and 2.664% w/w of gallic acid in the ethyl acetate extract. The commercial formulation shows 0.058% w/w of ellagic acid and 0.573% w/w of gallic acid in methanol extract and 0.422% w/w of ellagic acid and 1.637% w/w of gallic acid in ethyl acetate extract. Linearity studies indicated that ellagic acid and gallic acid were in the linear range of 125-500 ng and 1.25-5.00 μg, respectively, while the % recovery studies revealed a recovery of 99.2% w/w of ellagic acid and 98.13% w/w of gallic acid, thus proving the accuracy and precision of the analysis. Since this method resolves and quantifies ellagic acid and gallic acid effectively, it can be used to quantify the concentration of both the active principles in the herbal formulations.

Comparative Phycochemical Investigation of Hydrocarbons Content on Some Marine Seaweeds Algae

Isolated hydrocarbons from three green algae (Enteromorpha intestinales, Ulva rigida and Ulva fasciata) and one red alga Hypnea cornuta were qualitatively and quantitatively analysed using Gas-Liquid Chromatography (GLC) technique. Eighteen hydrocarbons in the four specimens of seaweeds namely; dodecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, nonadecane, eicosane, hencosane, docosane, tricosane, tetracosane, pentacosane, hexacosane, heptacosane, octacosane, nonacosane and triacontane were registered. Ulva fasciata was characterized by the presence of triacontane (73.38%) while it disappeared from the other selected algae specimens. Docosane was found in all selected algae with high percentages; Enteromorpha intestinales (39.99%), Hypnea cornuta (32.17%), Ulva fasciata (16.22%) and Ulva rigida (10.61%). Octacosane content showed its maximum value 83.03% in Ulva rigida. Dodecane recorded its highest concentration in Enteromorpha intestinales (31.11%). The data analysis indicates that the selected species are polluted samples and can be used as bioindicators of pollution.

Comparative Phytochemical Investigation of Beneficial Essential Fatty Acids on a Variety of Marine Seaweeds Algae

The methyl esters from the extracts of three green algae (Enteromorpha intestinales, Ulva rigida and Ulva fasciata) and one of red alga Hypnea cornuta were qualitatively and quantitatively analysed through GLC technique. A wide variety of saturated and unsaturated fatty acids were detected. Fourteen fatty acids in the four specimens of seaweeds registered namely, capric, lauric, tridecanoic, myristic, myristoleic, palmitic, palmitoleic, stearic, oleic, linoleic, linolenic, arachidic, arachidonic and eicosapentanoic. The total sum of the recorded fatty acids increase in the order: Enteromorpha intestinales < Ulva rigida <>

Piptadenol A-C and α-Glucosidase Inhibitor From Piptadenia africana

Ten compounds were isolated from the CH2Cl2/MeOH (1/1) stem bark extract of Piptadenia africana, a western Cameroonian plant species. These compounds included three new lactone derivatives piptadenol A-C. The known compounds include 5,6-dimethoxy-7-hydroxyflavone, antiquol B, sistosterol, β-amyrine, betulinic acid, cholesterol and 24(S)-stigmat-5,22-dien-3β-O-glucopyranoside. The latter was found to be highly promising α-glucosidase inhibitor. These compounds were characterized using physical and spectroscopic methods. The plant extract and 24(S)-stigmat-5,22-dien-3 β-O glucopyranoside showed antibacterial activity.

Comparative Assessment of Antifungal Activity of Extracts from Eucalyptus globulus and Eucalyptus citriodora

A study was conducted to establish the antifungal properties of extracts from Eucalyptus citriodora and Eucalyptus globulus. Three fungal pathogens were identified and used in this study, Trichophyton mentagrophytes, Microsporum gypsum (filamentous forms) and Candida albicans (yeast) using the well diffusion method. Serial dilution of the extracts and essential oils was done in order to determine the lowest active concentration in comparison to that of 1% Clotrimazole, 50 mg mL-1 Griseofulvin and 1% life Nystatin. The activity of 100 and 50% of E. citriodora oil was greatly higher than that of E. globulus and standard drugs. Methanol extracts were less active, compared to essential oils (p< style=""> chromatogram analysis of E. citriodora oil confirmed a total of 9 compounds. The E. citriodora oil presented the highest growth inhibition for all the microorganisms tested. The results indicate that E. citriodora and E. globulus have some antifungal properties which might be exploited as natural fungicide for the management of fungal diseases especially in this era of opportunistic diseases due to HIV/AIDS.

Occurrence, Uptake, Accumulation and Physiological Responses of Nickel in Plants and its Effects on Environment

Literature pertaining to the uptake and accumulation of Nickel (Ni) in plants and its effects on physiology and biochemistry in plants has been reviewed. The review shows that Ni has significance as a nutritive as well as a potentially toxic element in the plants and environment.

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Sunday, June 15, 2008

Cardiovascular Surgical Procedures

Cardiovascular Surgical Procedures

Over 2500 publications are available on cardiovascular surgical procedures. They can be accessed from:

http://www.ahajournals.org/cgi/bbtBrowse?subdir_name=ahajournals_bbt&category=3163196

Here are some article links.


Subodh Verma, Paul W.M. Fedak, Richard D. Weisel, Jagdish Butany, Vivek Rao, Andrew Maitland, Ren-Ke Li, Bikramjit Dhillon, and Terrence M. Yau
Fundamentals of Reperfusion Injury for the Clinical Cardiologist

Circulation 2002 105: 2332-2336. [Full Text] [PDF]

JD Marsh and TS Smith
Calcium overload and ischemic myocardial injury

Circulation 1991 83: 709-711. [PDF]

Sanjiv Kaul
Assessing the Myocardium After Attempted Reperfusion : Should We Bother?

Circulation 1998 98: 625-627. [Full Text] [PDF]

M Galinanes, CS Lawson, R Ferrari, GA Limb, NW Derias, and DJ Hearse


Jakob Vinten-Johansen, Derek M. Yellon, and Lionel H. Opie
Postconditioning: A Simple, Clinically Applicable Procedure to Improve Revascularization in Acute Myocardial Infarction

Circulation 2005 112: 2085-2088. [Full Text] [PDF]

H.E. Cingolani, I.L. Ennis, and S.M. Mosca
NHE-1 and NHE-6 Activities: Ischemic and Reperfusion Injury

Circ. Res. 2003 93: 694-696. [Full Text] [PDF]


Luca Regli, Robert E. Anderson, and Fredric B. Meyer


LD Horwitz, PV Fennessey, RH Shikes, and Y Kong



Y Kusama, M Bernier, and DJ Hearse



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Arterial Blood Gas Video

Arterial Blood Gas Video


http://www.youtube.com/watch?v=stxntv0KkBE

Clinical image CD

Clinical image CD

Very useful CD for medical students and any one preparing for internal medicne exams.
It provides clinical images with different varieties in all branches of internal medicine, e.g., ECG's, blood films, x-ray's, neuro imaging, urinary microscopies, and pathologic microscopies.
The slide shows are accompanied by descriptive voice comments and explanations with board exam tips.

rared file in 4 parts (42mb*3+16mb)

http://rapidshare.com/files/83140079/Clinical_Images.part1.rar
http://rapidshare.com/files/83382515/Clinical_Images.part2.rar
http://rapidshare.com/files/83510251/Clinical_Images.part3.rar
http://rapidshare.com/files/83331041/Clinical_Images.part4.rar



 



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